Mart Loog

Research:

The topic of research is signal transduction in cells using multi-phosphorylation of proteins. As a model system, we use the main regulators of the cell cycle, cyclin-dependent protein kinases (CDK).

CDKs are enzymes that add encoded phosphate patterns to hundreds of target proteins and thereby act as precisely timed molecular switches at different stages of the cell adhesion process. We use the found laws to design de novo signal processors based on muli-phosphorylation, which would have wide application possibilities in the field of synthetic biology.

Additional information:

• Lab's webpage
• C E L E S T I A L
• www.woodbiotech.ee